Friday, February 24, 2012

Food and drug administration recommends ...

The key to good care of osteoporosis understanding of the causes of osteoporosis and, knowing the risk of fractures. The presence of bone mineral density test shows Dara important information on the risk of fractures (see


).

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Prevention of osteoporosis and treatmentinclude exercise and proper amount of calcium in your diet. Most adults over age 50 need 1200 mg per day, although you may need more if you have osteoporosis. Calcium supplements may be needed if your diet does not provide enough calcium to keep your bones strong. Taking too much calcium, however, may increase the risk of kidney stones. Vitamin D helps the body absorb calcium. Most adults do not have enough vitamin D in the body. Older men and women are likely to take vitamin D supplements. Current recommendations for the 800 to 1000 IU (international units) vitamin D3 per day. Young men and women may need to take vitamin D supplements, too. Very high doses of vitamin D can cause serious health problems so talk with your doctor about how much to you. Well-balanced diet with calcium-rich foods and calcium and vitamin D supplements, however, may not be enough to protect bones and prevent osteoporosis in all people. Each person and family health history is different, so the risk for bone fracture is different for each person. Some people may have to take medication for the treatment of osteoporosis. Food and Drug Administration (FDA) has approved several drugs to prevent and treat osteoporosis. These drugs include:


Bisphosphonates: Alendronate, ryzedronat, Ibandronat, zoledronovoyi acid


Bisphosphonateswhich brake failure boneare used to prevent and treat osteoporosis, slowing bone loss while increasing bone mass. Bisphosphonates help to reduce the risk of spine, no spine and hip fractures. Alendronate, and ryzedronat zolderonic acid is also approved for the treatment of steroid-induced osteoporosis in men and women who require long-term use of drugs to treat inflammatory diseases (which can contribute to osteoporosis). If you are taking oral bisphosphonates, you must take medication on an empty stomach arising in the morning with a full glass of water. Stay upright after taking the dose. If you take alendronate or ryzedronat lasix generic no prescription not drink or eat anything for the next 30 minutes, so your body uses drugs. If you take ibandronat, you must wait 60 minutes to eat or drink anything. Side effects of bisphosphonates are rare but may include abdominal, bone or muscle pain. These drugs also may cause nausea or heartburn. Stimulation of the esophagus can occur with a tablet form of this drug. Relatively high doses, bisphosphonates long-term therapy that may be introduced during cancer treatment, for example, was associated with osteonecrosis (degeneration) jaw bone. This problem usually occurs most often after dental operations. There is an assumption that some very rare degeneration of the jaw can also develop after relatively low doses, long-term treatment of bisphosphonates in the mouth. This is an area of ​​active research studies. Bisphosphonates are not recommended to menopausal women who may become pregnant. Calcitonin is a natural hormone produced by specialized cells in the thyroid gland. However, parathyroid hormone, calcitonin helps to regulate calcium levels in the body. Calcitonin, which is given as a nasal spray, has been shown to modestly increase bone density and may reduce the risk of fractures of the spine. His influence on bone building, usually less than other approved therapies. Side effects of nasal calcitonin are rare but may include nasal irritation, back pain, bloody nose, and headaches. Election Estrogen Receptor Modulators (SERMs): Raloksifen raloksifen approved for the prevention and treatment of osteoporosis in postmenopausal women. It is in a class of drugs called selective estrogen receptor modulators (SERMs). These estrogens as drugs have been developed for the benefit of bone, avoiding the potential risks associated with estrogen therapy (such as increased risk of breast cancer or heart disease). Raloksifen increases bone density and reduces the risk of fractures of the spine, but it has not been shown to reduce the risk of non-spine fractures. Raloksifen also reduces the risk of invasive breast cancer. Raloksifen taken in pill form once a day, with or without food. Although rare, side effects may include hot flashes, cramping calf muscles, or blood clots in the legs and lungs. Raloksifen not recommended in premenopausal. Teriparatide Teriparatide is a fragment or part of the full-length parathyroid hormone molecule, which is a natural hormone involved in calcium regulation. Teriparatide stimulates the formation of a new procedure for bone, rather than fighting bone breakdown. Because of potential safety problems, the use of this drug is limited to men and women with severe osteoporosiswho have a high risk fractureand may be given to two years. Teriparatide is given as a daily self-injection. Side effects are rare but may include seizures, headaches and dizziness. This drug is not recommended in premenopausal. Estrogens Estrogens can be taken separately or in combination with progestin, a synthetic form of female hormone progesterone, which helps protect against uterine cancer. (If your uterus has been removed by surgery, you should not take progestin with estrogen).


Hormone estrogen therapy prevents bone loss and reduces the risk of fractures in the spine and hip. It can also remove other symptoms of menopause such as hot flashes and vaginal dryness. Estrogen is usually given in pill form, although it is also available in other forms such as a patch or gel. Recent studies have shown that the risk of estrogen therapyincluding heart attack, stroke, blood clots and breast canceroutweigh its benefits in most women. For this reason, estrogen therapy is no longer considered suitable only for the prevention of fractures. In fact, even when estrogen is used to treat symptoms of menopause, the U.S. Food and Drug Administration recommended it as a low dose for as short time as needed. Each of these drugs has certain advantages and side effects. You should work with your doctor to find the treatment that is right for you. To find an endocrinologist, please visit our physician directory areas. Alendronate, ryzedronat, zoledronovoyi acid and teriparatide was approved for the treatment of osteoporosis in men. Although there are fewer studies in men, the effects of these drugs on bone mass similar to their effects in women and is likely to be useful in treating men with osteoporosis. The question that testosterone is useful for the treatment of osteoporosis in men remains controversial. In men who clearly have low testosterone levels, testosterone therapy seems to increase bone density. Because testosterone levels tend to decrease with age, many older men testosterone levels that are low. Testosterone supplements may increase bone mineral density in these men as well, but the dose needed and the best way to manage this treatment is not clear. There is no information about the treatment of testosterone in men is effective in reducing the risk of fractures. Finally, long-term risks of testosterone therapy in older men are unknown. Now, do not usually recommend using testosterone as a primary treatment of osteoporosis in men. It is important to remember that the approved treatment of osteoporosis for women (alendronate, ryzedronat, zoledronovoyi acid and teriparatide) seems to be effective in men with low testosterone. .

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